Electrochemically Gated Graphene Field-Effect Transistor for Extracellular Cell Signal Recording

نویسندگان

  • Sanaz Asgarifar
  • Henrique L. Gomes
  • Ana Mestre
  • Pedro Inácio
  • José Bragança
  • Jérôme Borme
  • George Machado
  • Fátima Cerqueira
  • Pedro Alpuim
چکیده

This work presents an experimental characterization of electrochemically gated graphene field-effect transistors (EGFETs) to measure extracellular cell signals. The performance of the EGFETs was evaluated using cardiomyocytes cells. Extracellular signals with a peak value of 0.4 pico-amperes (pA) embedded in a noise level of 0.1pA were recorded. Signals in current mode were compared with signals recorded as a voltage. Signals below 28 μV of magnitude can be detected in a noise floor of 7 μV with a signal-to-noise ratio of 4.

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تاریخ انتشار 2016